Toxicology studies in evolution
Auteur: Koen Van Deun ea
ISBN: 9789035613621
Aantal pagina's: 315p
Prijs:
In this book you will be introduced to the major toxicology domains, principles and mechanisms, which provide a general un-derstanding of toxicology. Further, a struc-tural summary is given of the various toxico-logical endpoints and assays required for the development and registration of safe medicines, chemicals and other product types, followed by assay examples which have been elaborated textually and sche-matically. In addition, the evolution and sta-tus of toxicological methods from in vivo to in vitro and in silico approaches is given. Finally, some clinical, analytical and foren-sic applications of toxicology have been described.
Over de auteur
Koen Van Deun is a veterinarian and toxicologist and worked as a researcher at the University of Ghent and as a principal investigator at Johnson & Johnson Pharmaceuticals R&D (former Janssen Pharmaceutica) in the general and in vivo toxicology department. Since 2001, he has been active as independent adviser in toxicology and quality, and also as lecturer in toxicology & quality at the Life Sciences & Chemistry Unit at the Thomas More University of Applied Sciences in Geel.
Philippe Vanparys is a biologist and toxicologist and headed the function of senior research fellow and senior director at Johnson & Johnson Pharmaceuticals R&D (former Janssen Pharmaceutica) in the genetic and in vitro toxicology department and then founded a new group for mechanistic in vitro toxicology, including irritation & sensitization studies. Afterwards he has been active as a consultant and guest lecturer at national and international courses.
Riet Van Deun is a bioengineer and started as a project manager toxicology & quality at Reflector Consulting. Since 2023, she became independent and was also certified as toxicologist, focussed on the risk evaluation of various products by literature search, in silico toxicology and read-across applications in addition to experimental data. In addition, she is also active in the quality assurance of toxicology and safety studies.